Meet Dr. Derek Guillory
Derek W. Guillory, MD, is a board-certified physician and the founder of Root Causes Medicine. As a child and teenager, Derek experienced persistent, unexplained health problems that led him to question how the body breaks down and what allows it to recover. Those early experiences shaped his path in medicine. Over time, Derek developed a structured approach to understanding illness focused on identifying what interferes with normal physiology and what the body needs to repair and regulate itself. Root Causes Medicine reflects that work: a clear framework designed to explain why symptoms persist and how health can improve through measurable change.
A Physician Focused on
Explanation, Not Assumptions
“We start with a simple question: why is the body struggling?
When someone comes in with persistent symptoms, our goal is to understand what’s happening beneath the surface. We look at how environmental exposures, nutrient status, stress physiology, and daily inputs interact over time. Patterns matter. Context matters. Progress depends on identifying what is interfering with normal function and what the body needs in order to recover.
At Root Causes, we help people understand where to focus, what to address first, and how to track change without unnecessary complexity. This way of working stays medical, practical, and evidence-aligned. It emphasizes explanation, measurable inputs, and thoughtful action so patients can move forward with confidence.”
–Derek
The Root Causes Medicine Framework
Root Causes Medicine is built on a simple principle: health declines when harmful inputs accumulate and restorative capacity falls short. Everyday exposures—air, water, food quality, household products, and chronic stress—quietly add load to the system, while nutrient gaps and physiological strain reduce the body’s ability to repair. Fragmented care treats symptoms; Root Causes Medicine connects patterns. Using structured, stepwise protocols, our doctors help patients lower unnecessary burden, replenish what’s missing, and track progress over time.
Unfiltered Health Wisdom from Dr. Derek Guillory
Dr. Guillory is committed to making this way of thinking accessible beyond patient visits. Through the Root Causes newsletter, educational writing, and an upcoming book, he translates complex science into practical understanding. His goal is to help people think clearly about health before problems become entrenched.
Join thousands discovering the root causes of chronic illness and reclaiming their health through functional medicine insights you won’t find anywhere else.